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IAS 2017: TAG Releases Annual HIV, Hepatitis C, and TB Pipeline Report

On July 18 the Treatment Action Group (TAG) announced the launch of its latest overview of investigational therapies for HIV, hepatitis C virus (HCV), and tuberculosis (TB).

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IAS 2017: IAS Conference on HIV Science Starts Sunday in Paris

The 9th International AIDS Society (IAS) Conference on HIV Science will take place July 23-26 at the Palais des Congrèsin Paris. HIVandHepatitis.com and aidsmap will be providing joint on-site coverage next week. Follow breaking news via @HIVandHeptitis on Twitter. IAS will be webcasting plenary sessions and daily press conferences.

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CROI 2017: Accelerated Linkage to HIV Care Improves Retention by a Third

Close to 60% of adults benefitting from point-of-care CD4 cell count testing at HIV testing sites, accelerated antiretroviral therapy (ART) initiation, and SMS appointment reminders were retained in care after 1 year, compared to just 44% of those receiving the standard of care in Mozambique, according to findings from the Engage4Health study presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2017) in Seattle.

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HR17: Combining Drug Addiction Treatment and Perinatal HIV Prevention Leads to Good Outcomes

An integrated program offering medication-assisted drug addiction treatment and services aimed at preventing mother-to-child HIV transmission led to improved outcomes for opioid-dependent HIV-positive mothers and their babies, according to a presentation at the 25th Harm Reduction International Conference this month in Montreal.

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CROI 2017: Test and Treat Study Shows Second Phase Is Finding More People with HIV

After a second wave of intensive household testing, a large study of the "test and treat" strategy in Zambia is diagnosing more people with HIV, getting more people onto treatment, and reducing the time between diagnosis and starting treatment, findings from the PopART study presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2017) show.

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CROI 2017: 1 in 5 HIV+ Men in U.K. Who Say They Are Heterosexual Caught HIV from Another Man

A genetic analysis of a large database of people with HIV in care in the U.K. shows that 18% of HIV-positive men who claim to be exclusively heterosexual in fact belong to clusters of linked infections that consist only of men. The data were presented by Manon Ragonnet-Cronin and colleagues from Edinburgh University at the recent Conference on Retroviruses and Opportunistic Infections in Seattle.

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Coverage of the 2017 Harm Reduction International Conference

HIVand Hepatitis.com coverage of the 2017 Harm Reduction International Conference, May 14-17, 2017, in Montreal.

Full coverage listing

HR17 website

5/31/17

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CROI 2017: Simple Risk Score Can Identify Gay Men Who May Have Acute HIV Infection

A set of 7 simple questions about symptoms and risk factors identified three-quarters of gay men in Amsterdam who have acute (very recent) HIV infection, according to a study presented at the Conference on Retroviruses and Opportunistic Infections in Seattle last month. Using this risk score could identify gay men requiring HIV RNA testing, which can detect acute infections, in addition to HIV antibody testing.

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PAS 2017: Many Doctors Wary of Providing PrEP for Young Patients

Only about a third of family practice and pediatric providers said they would be likely to prescribe HIV pre-exposure prophylaxis (PrEP) to adolescent patients, underlining the need to educate providers outside the HIV and sexually transmitted disease fields, according to a report at the 2017 Pediatric Academic Societies Meeting last week in San Francisco.

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CROI 2017: Better Depression Care Could Improve Outcomes for HIV Treatment Programs

Improved management of depression and other mental health problems has the potential to improve the outcomes of HIV treatment programs, Pamela Collins of the U.S. National Institute of Mental Health reported at the recent Conference on Retroviruses and Opportunistic Infections in Seattle. Mental health treatment should be integrated into HIV services in resource-limited settings, she said.

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Coverage of the 2017 Conference on Retroviruses and Opportunistic Infections

HIVandHepatitis.com coverage of the 2017 Conference on Retroviruses and Opportunistic Infections, February 13-16, 2017, in Seattle.

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Antiretroviral Therapy and Treatment Strategies

HIV Cure Research

HIV Prevention

HIV-Related Conditions and Complications

HIV Epidemiology and Access to Care

Hepatitis C and HIV/HCV Coinfection

Tuberculosis

 

CROI 2017: Peer Navigators Improve Linkage to HIV Care and Retention in South African Study

Adults recently diagnosed with HIV who get help from peers to address personal barriers to care together with SMS check-in messages, appointment, and healthy living reminders had nearly twice the odds of being retained in care at 1 year of follow-up compared to those getting standard care at primary health clinics in South Africa according to findings presented at the recent Conference on Retroviruses and Opportunistic Infections.

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Coverage of the 2017 Conference on Retroviruses and Opportunistic Infections

HIVandHepatitis.com coverage of the 2017 Conference on Retroviruses and Opportunistic infections (CROI 2017), February 13-16, 2017, in Seattle.

Full coverage listing by topic

CROI website

4/16/17

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CROI 2017: Finding Men with HIV -- and Keeping Them in Treatment

Specialized services to attract men to HIV testing and treatment may need to adopt several different formats in order to reach different sub-populations of men, suggesting there is no single service innovation that will boost uptake among men in sub-Saharan Africa, according to research from South Africa presented at last month’s Conference on Retroviruses and Opportunistic Infections.

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Obituary: Pioneering HIV Researcher Mark Wainberg

Mark Wainberg, a highly regarded clinician and researcher who helped advance HIV therapy and advocated for access to treatment and care worldwide, died on April 11 in a swimming accident in Florida at age 71.

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CROI 2017: How Does Vedolizumab Antibody Therapy Lead to Sustained Viral Remission?

HIV and its monkey cousin SIV can carry the alpha-4 beta-7 integrin receptor in their outer envelope, which helps the virus enter gut cells during early infection, according to research presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle. This finding may help explain how an antibody against alpha-4 beta-7 produced sustained viral remission in monkeys.

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HIV PrEP Is Approved in Scotland

The Scottish Medicines Consortium (SMC) announced this week that it had accepted tenofovir disoproxil fumarate/emtricitabine (Truvada) for use within the Scottish National Health Service as pre-exposure prophylaxis (PrEP) to prevent HIV infection.

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CROI 2017: Bone Density Improves in People Who Switch from Tenofovir DF to Tenofovir Alafenamide

After 3 years, tenofovir alafenamide (TAF) for first-line HIV treatment was better at suppressing viral load and safer for the bones and kidneys than the older tenofovir disoproxil fumarate (TDF), researchers reported at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) last month in Seattle. Another study showed that people with low bone density who switched from TDF to TAF saw improved bone health, including a reduction in osteoporosis.

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BHIVA 2017: Large Fall in London HIV Diagnoses Is Due to Combination Prevention, Not Just PrEP

The number of new HIV diagnoses among gay men attending 5 key London clinics fell substantially during 2015 and 2016, Valerie Delpech of Public Health England reported at the British HIV Association (BHIVA) conference last week in Liverpool.

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CROI 2017: Long-Term Darunavir/Ritonavir Modestly Increases Risk of Cardiovascular Disease

Long-term use of the boosted protease inhibitor darunavir (Prezista) modestly increases the risk of cardiovascular disease, according to data from the ongoing D:A:D study presented to the recent Conference on Retroviruses and Opportunistic Infections. Investigators identified an independent association between cumulative use of the drug over 5 years and heart attack and stroke.

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